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We provide here additional evidence, notably from redox proteomic approaches that most if not all enzymatic steps of the reductive sulfate assimilation and of methionine synthesis pathways may be controlled by oxidative modification of the enzymes, primarily protein persulfidation but also, disulfide bond formation, protein sulfenylation, nitrosylation, and glutathionylation to a lesser extent

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Undoubtedly, ArnT constitutes a promising therapeutic target for overcoming polymyxin resistance

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