Supraventricular Tachycardia (SVT) : This is a very fast but regular heart rhythm that starts in the upper chambers
Using human brain organoid models derived from induced pluripotent stem cells (iPSCs) with targeted knockout of the CNTNAP2 gene, which is associated with autism spectrum disorder (ASD), it was revealed that CNTNAP2-deficient brain organoids exhibit abnormalities such as accelerated cell cycle, increased cortical folding, disrupted glutamatergic/GABAergic synaptic pathways, and upregulation of AKT/mTOR signaling (106)
Alesci S, Martinez PE, Kelkar S, Ilias I, Ronsaville DS, Listwak SJ et al
doi: 10.1038/s41389-020-0200-9 13 ZhuSLiuYChenHZhuXLiuXXuKet al
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