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The critical question lies in determining whether elevated circulating metabolite concentrations represent disease-driving factors or secondary manifestations of excretory dysfunction
Fernndez-Checa, Liver Unit, Hospital Clnic, Centre Esther Koplowitz, Institut dInvestigacions Biomdiques August Pi i Sunyer (IDIBAPS)Centro de Investigacin Biomdica en Red de Enfermedades Hepticas y Digestivas (CIBERehd), Planta Cuarta, C/Rossell 149, Barcelona 08036, Spain e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a Section of the journal Frontiers in Pharmacology
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Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat
This means that the root cause of PCOS (at least the majority of it) is insulin resistance, and this is why metformin is so commonly used to treat it
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