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Description

Within the GHSR1a-MC3R dimer, the GHSR1a inverse agonist SP-analog eliminates amplification of MC3R signaling (Rediger et al., 2011), an effect likely due to the dependence on GHSR1a constitutive activity

A three-year study of patients receiving regular Epithalon courses observed no adverse effects in the treatment group, with significantly reduced mortality compared to control groups