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These pre-existing conditions may flare up coincidentally during treatment, leading patients to wonder if the medication is responsible

While prioritizing protein is important for maintaining muscle mass during weight management, its important to pair it with fiber-rich foods to support digestion

Dose escalation can be delayed by 4 weeks if adverse effects persist, and treatment is not recommended for patients with severe gastrointestinal disease

Notably, in the condition of excess hemin exposure and hypoxia, our findings suggest an important contribution of the TSS pathway and its regulation by DMF for de novo cysteine synthesis and GSH generation in protecting against the oxidative and ferroptotic stresses in SCD erythroblasts

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