semaglutide and oral birth control Wegovy Pill Becomes First GLP-1 Weight-Loss Drug Approved in U.S Contraception warning over weight-loss drugs

J., Linge, J., Birkenfeld, A

These peptides work through multiple mechanisms including enhanced blood flow to reproductive organs, reduced inflammation in testicular tissue, and improved cellular repair processes that directly impact sperm development and maturation

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This may relate to progesterones effects on gastric motility during the luteal phase, which already slows digestion independently of the medication

[1] [4] Semaglutide activates the same GLP-1 receptors as the endogenous hormone, producing comparable physiological effects but with sustained duration