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However, individuals with absorption disorders may require significantly higher doses to achieve therapeutic levels

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Vitamin B12 is essential during pregnancy and breastfeeding for fetal neurological development and maternal health

pre- and post-operative treatment, when requirements are increased as in fever, severe burns, increased metabolism, pregnancy, gastrointestinal disorders interfering with intake or absorption of vitamins, prolonged or wasting diseases, alcoholism and where other deficiencies exist

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