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Lipoproteins such as Low-density lipoproteins (LDL) and high-density lipoproteins (HDL) are mainly responsible for the transport of lipids such as cholesterol and triglycerides (117)
One possible route of this accumulated astrocytic iron is the extracellular space via FPN, where astrocyte-derived iron can be used by OPCs and microglia in the process of remyelination (65)
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Following a 2-month washout period, the mean MDS-UPDRS motor scores in the off-medication state were 2.9 points higher in the placebo group, underscoring the potential benefits of lixisenatide in early PD [100]
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