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Neurogenic Differentiation and Epigenetic Gene Regulation A more recent and mechanistically distinct research domain for the AEDG sequence involves its effects on gene expression during neurogenesis

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Characterization of procaspase-1 cleavage in mammalian cells To determine whether X(PC) can cleave full-length procaspase-1 in a cellular context, we transfected hemagglutinin (HA)-tagged procaspase-1-Cys285Ala into HEK293T cells and incubated lysates with decreasing doses of purified proteases (Extended Data Fig

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