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This article reviews current evidence, evaluates pharmacological and mechanistic safety profiles, summarizes recent cohort studies, and discusses clinical management strategies for preconception counselling and inadvertent exposure

Instead, it works primarily by modulating inflammation, promoting blood vessel formation, and supporting the healing of surrounding soft tissues

Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway

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Peptide drugs that target local inflammation and angiogenesis demonstrate reduced lesion size in animal models and early human safety data