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Proc Natl Acad Sci USA 1986
These hormonal adjustments can be slow, and many patients may only begin seeing substantial weight changes after consistent, prolonged use
* Of the 6,990 deaths that occurred among the volunteers, 43.3 percent resulted from heart disease or a stroke
Common experiences during weeks 1-2 include mild nausea (reported by approximately 14% of participants at the 1 mg dose level), slight changes in appetite timing, increased awareness of fullness cues, and occasional fatigue as the body processes a new metabolic signal
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