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In some cases, taking very high doses for a long period can cause a mild, harmless yellowish tint on the palms of your hands or soles of your feet

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Oxidative Med Cell Longev Chen J, Marks E, Lai B, Zhang Z, Duce JA, Lam LQ, Volitakis I, Bush AI, Hersch S, Fox JH (2013) Iron accumulates in HD neurons: protection by deferoxamine

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