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Phase 2 clinical trials published in 2023 reported mean resting heart rate increases of approximately 5 to 7 beats per minute at higher doses (8 mg and 12 mg weekly)
Last reviewed: June 12, 2026 Last updated: June 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Try two or three bouts of weekly strength training or moderate-intensity cardio like walking uphill, jogging, or circuit training
The findings were published recently in Nature Communications
