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[2] However, unexplained elevation warrants investigation for underlying pathology, particularly hepatic or haematological disease

The GLP-1 agonists used were liraglutide (57.3%), followed by semaglutide (32.9%), dulaglutide (4.9%), exenatide (4.1%), and lixisenatide (0.9%)

This difference may be due to the estimand choice of Pan et al., which is not reported, and the influence of additional studies that did not match our target population as Pan et al.s NMA had much broader eligibility criteria, with some studies including participants with T2D or using intensive behavioural therapy

Conclusion Heres the thing, affordability and safety can both matter