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DPP-9 belongs to the same family as DPP-4, and it is known that saxagliptin is a less selective inhibitor, whereas sitagliptin is highly selective for DPP-4 (35) and does not alter DPP-9 activity (136)
After all, the meds are supposed to squelch hunger, cause you to undereat, and lead to weight loss
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In physiological conditions, the cytotoxic potential of ROS is controlled by a variety of mitochondrial, cytosolic, and peroxisomal antioxidant systems, including superoxide dismutases (SODs), CATs, peroxiredoxins, thioredoxin, glutathione (GSH), and thiol-containing proteins [24]
![Classification of GLP-1 RAs based on different parameters [13]](https://www.researchgate.net/publication/343265981/figure/tbl1/AS:923164464906240@1597110968484/Classification-of-GLP-1-RAs-based-on-different-parameters-13.png)
