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J Clin Investig 116:25712579 Bianco AC, Salvatore D, Gereben B et al (2002) Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
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For GLP-1 RA therapy, this implies that weight loss in this population likely derives primarily from appetite suppression rather than from correcting pre-existing metabolic abnormalities, informing expectations about therapeutic mechanisms and outcomes
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