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Department of Medicine, University Medical Centre Mainz, Johannes Gutenberg University, Mainz, Germany, Mainz, Germany, (4)University of Texas Southwestern Medical Center, (5)Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom, (6)Houston Research Institute, Houston, TX Background: Nonalchoholic fatty liver disease (NAFLD) and its severe form, nonalcoholic steatohepatitis (NASH), are associated with obesity, type 2 diabetes, and metabolic syndrome
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In mouse models of Alzheimer's disease, systemic administration of GHK-Cu for 12 weeks results in 30% improvement in cognitive function tests and 25% reduction in brain amyloid plaque burden compared to vehicle-treated controls
