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ITPP enters red blood cells and binds to the same allosteric site as 2,3-bisphosphoglycerate (2,3-BPG), shifting hemoglobin toward the T-state that favors oxygen release (Zhang et al., 2024)
Requires short-horizon biomarker readouts (ApoB, hsCRP, CGM variability, MRI-PDFF, FMD) and robust outcomes trials to validate
Less muscle tissue automatically means a much slower resting metabolism because muscle tissue burns significantly more calories than inert body fat readily
Patients using Ozempic typically experience significant reductions in HbA1c levels and weight, alongside improvements in cardiovascular health
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