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Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease

The second group followed a stop-and-start cycle (two weeks on, two weeks off the drug) for three cycles before switching to consistent use for the final two months

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In the first Phase 3 trial, participants on the highest dose lost an average of 29% of their body weight over about 16 months