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The production of MDA and ROS during ferroptosis triggers significant oxidative stress and inflammation (Yuan et al., 2024)

37 ClinicalTrials.gov NCT03648281

Food and Drug Administration (2021) Dietary guidelines for Americans, 2020-2025, USDA (2020) Calorie calculator, Mayo Clinic Counting calories: Get back to weight-loss basics, Mayo Clinic Saturated fat, American Heart Association The evidence for saturated fat and for sugar related to coronary heart disease, Progress in Cardiovascular Diseases (2024) Could a diet high in carbohydrates increase your risk of heart disease?, News Medical (2021) Get the facts: Sugar-sweetened beverages and consumption, Centers for Disease Control and Prevention (2022) The effects of alcohol consumption upon the gastrointestinal tract, American Journal of Gastroenterology (2000) Consumption of ultra-processed foods and health outcomes: A systematic review of epidemiological studies, Nutrition Journal (2020) A new medication for weight loss, Cedars-Sinai (2021) Clinical evidence and mechanisms of high-protein diet-induced weight loss, Journal of Obesity and Metabolic Syndrome (2020) Increased protein intake reduces lean body mass loss during weight loss in athletes, Medicine & Science in Sports & Exercise (2010) Role of calcium and low-fat dairy foods in weight-loss outcomes revisited: Results from the randomized trial of effects on bone and body composition in overweight/obese postmenopausal women, Nutrients (2019) The relationship between whole grain intake and body weight: Results of meta-analyses of observational studies and randomized controlled trials, Nutrients (2019) Legume intake, body weight, and abdominal adiposity: 10-year weight change and cross-sectional results in 15,185 U.S

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3.1 Concept of pre-asthma Pre- asthma could be defined as a state in which the subject is experiencing mild, probably intermittent lower airways inflammation/ hypersensitivity which is insufficient to cause symptoms, but which is capable of progression to asthma