By stimulating the release of HGH
Anecdotally, I have heard him say that he has to go as far as recommending protein supplementation2 to patients who are clearly not eating more than 500 calories a day, simply because they do not have the appetite to.3 Patients who, before they were on these drugs, consumed upwards of 5000 calories a day
Instead of titrating to the full doses recommended for obesity treatment (e.g., semaglutide 2.4 mg weekly or tirzepatide up to 15 mg), microdosing involves starting and staying at much lower doses sometimes as low as 0.1 to 0.25 mg per week for semaglutide or even intermittent use
(PubMed) McGarry A, McDermott M, Kieburtz K, et al
My doctor chased me for two years, and I was like, No Im afraid of it. I already have thyroid problems, I was afraid, Clarkson said