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Practical management strategies include: Gradual dose titration : Following the recommended titration schedule allows the gastrointestinal system to adapt

The goal of adding GH secretagogues is shifting the weight loss composition toward fat loss and away from muscle loss, not preventing weight loss

Therapeutic strategies targeting mitochondrial dysfunction for comorbidity intervention (Table 2) Enhancing mitochondrial energy metabolism Mitochondrial protectants Coenzyme Q10, a well-established clinical therapeutic agent, is a component of the ETC and plays a dual role in facilitating electron transfer and exerting potent antioxidant effects

Ways of treating xerostomia including stopping or reducing whatever may be inhibiting saliva production, using lozenges like ones that contain sorbitol or taking medication that stimulate saliva production like cevimeline and pilocarpine

Thorner, M