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Note: It is important to keep in mind that some of the biological activities discussed above were observed in cultured cells and animal models exposed to curcumin at concentrations unlikely to be achieved in cells of humans consuming curcumin orally (see Metabolism and Bioavailability)

These are typically mild to moderate and often subside over time, but they can be uncomfortable

Not always dramatic, but the trend is upward, and men report subjective improvements in energy, mood, and libido that correlate with these hormonal shifts

A generic can still face method-of-use exposure if dosing follows the claimed schedule

Studies are ongoing to obtain approval for type 2 diabetes treatment