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Ketoacidosis Farxiga may rarely cause a dangerous buildup of ketones in some people, though this is more likely in those with diabetes or pancreatic problems
P.FerreiraA
Cagrilintide differs from other peptides in several ways: Versus GLP-1 agonists (semaglutide, tirzepatide) Cagrilintide works through amylin rather than GLP-1 pathways, offering complementary rather than redundant mechanisms
The most common adverse events are gastrointestinal in nature, including nausea (20-47% depending on dose), constipation (21%), fatigue (20%), and vomiting (8%)
(FYI, participants were not on any other diabetes medications at the start of the trial.) Participants also had an average weight loss of 4.5%7.6% over the same period, with those who took higher doses experiencing the higher end of the range of weight loss
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