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However, morphological studies have demonstrated that cochlear development proceeds normally, and the gross morphology of the organ of Corti is normal, indicating that Lgr5 is dispensable for hair cell formation (Chai et al., Lgr5 -positive cells in the postmitotic neonatal cochlea that have garnered attention recently as a possible source of hair cell progenitors
Among these, BPC-157 and TB-500 have emerged as compounds of growing clinical and research interest due to their multifaceted therapeutic applications in tissue regeneration and cytoprotection
They are expensive because pharmaceutical manufacturers have spent billions of dollars on R&D to get FDA approval
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