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Genome Med 8(1):42
However, despite encouraging preclinical results, clinical translation remains limited and will likely require combined strategies that address both upstream immune dysregulation (to induce tolerance) and ongoing symptoms
EG3G refers to the active ingredient in green tea extract, which is scientifically known as epigallocatechin gallate, EG3G, or EGCG
This superior efficacy helped it achieve global sales of ~US$16.4bn in 2024 (Mounjaro ~US$11.5bn and Zepbound ~US$4.9bn), rivalling semaglutide and completely overshadowing the sales of historical GLP-1s, such as exenatide, liraglutide and dulaglutide [FIGURE TWO]
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