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10.1189/jlb.0403147 165 Zeichner-DavidM.ChenL

A reduction in the binding affinity of Insulin-like Growth Factor 1 Long Arg3 (IGF-1 LR3) for IGFBPs might potentially influence its bioavailability

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To ensure that this study was conducted as a single-regimen treatment, all enrolled patients were clearly instructed not to use any additional medications for CRS, including other nasal sprays, oral antihistamines, leukotriene modifiers, decongestants, or systemic steroids, throughout the entire 8-week treatment period