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Various factors, including idiopathic factors, genetic factors, iatrogenic factor, autoimmune diseases, infectious diseases, environmental toxicants, can induce accelerated activation or death of primordial follicles and accelerated atretic follicles, leading to premature ovarian insufficiency

If you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2), discuss the risks and benefits with your provider before starting

Vitamin C enhances anticancer activity in methotrexatetreated Hep3B hepatocellular carcinoma cells

What we care about most, though, are interventional studies, where people are randomized to B12 so we can see what happens