Discuss with your specialist or contact the Winnett team
Glucagon-like peptide 1 receptor (GLP-1R) is present not only in the central nervous system and gastrointestinal tract but also in the pancreas, kidney, lungs, cardiomyocytes, vascular smooth muscle cells, and endothelium [25,26,27,28,29]
As a consequence of the shortage situation, the Swedish Medical Products Agency published an open letter in November of 2023 urging healthcare professionals to only prescribe the drugs in question within the approved indication in order to ensure accessibility for diabetic patients [20,21,22]
This triggers the migration of occludin, which is another tight-junction complex, to the basolateral membrane
Patients and healthcare professionals should report suspected adverse drug reactions via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)