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Gastrointestinal eventssuch as nausea, diarrhea, vomiting, and constipationare the most common for both medications
Regulating blood sugar effectively
Our APAP model is a whole-body model of APAP that includes transport from the gut to the liver, the liver metabolism described in the previous paragraph, transport out of the liver to the blood, and excretion in the urine
Those who were moved to a placebo regained some weight even with continued lifestyle changes
After chronic treatment (completed by PND108), animals were euthanized, and blood and tissue samples were collected, processed, and properly stored until analyzed
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