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Binding of apoptosis-linked gene-2-interacting protein X to its N-terminal region promotes secretion, whereas keratin 20 binding at this region inhibits secretion and thereby prevents ferroptosis in kidney tubular cells [152]
Use in patients undergoing obesity-related weight loss treatment , including GLP-1 receptor agonists, dual agonists targeting GLP-1, GIP, and/or glucagon pathways, and triple agonists targeting GLP-1, GIP, and glucagon pathways
Latorre R, Huynh J, Mazzoni M, et al
10.3389/fphar.2018.00576 42
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