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Serious Side Effects Pancreatitis Risk: In rare cases, inflammation of the pancreas has been reported

A study presented at ENDO 2025 found that people taking semaglutide who consumed higher amounts of protein lost significantly less muscle mass than those who did not prioritize their nutrition

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If you're taking insulin or sulfonylureas (glipizide, glimepiride, glyburide, and similar), adding a GLP-1 medication increases your risk of hypoglycemia