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Overview Within the first 24 hours, GLP-1 worked almost too well, but in the days that followed, I learned that appetite suppression is only one part of the story
Specifically, treatment with exenatide acetate increased the ratio of p -AMPKThr172/AMPK, inhibited NF-B p65 phosphorylation, and downregulated pro-inflammatory markers, including IL-1 and TNF- [69]
however, the long-term safety profile remains undefined
The lead researcher in the study, Iain Campbell, PhD, research fellow in metabolic psychiatry at the University of Edinburgh in Scotland, appeared on Metabolic Mind to discuss the new study
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