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Doxorubicin stock solution (10 mM, 100% DMSO) was serially diluted in unbuffered seahorse assay medium to prepare 6 concentrations: 400, 300, 200, 100, 80 and 40 M
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In biochemical and cell-based laboratory studies, BPC-157 has been investigated for its interaction with several signalling pathways, including those associated with nitric-oxide-related processes, growth-factor signalling cascades and regulators of cytoskeletal dynamics
Rodent, goat, and petri-dish results establish biological plausibility and guide further research, but they routinely fail to translate to humans
In preclinical studies, the fragment C domain of the tetanus toxin (Hc-TeTx) has been shown to alleviate METH-induced neurotoxicity and motor deficits in animal models
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