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Positive inotropic effect: decreased ventricular diastolic pressure and the pre-ejection pd/LV ejection time ratio

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37 RCTs Meta-Analysis (2020) Weight loss: -1.13 kg BMI: -0.36 points Fat mass: -1.16 kg Waist circumference: -1.24 cm Umbrella Meta-Analysis (2025) Confirms: statistically significant weight loss , especially combined with exercise

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