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Its enhanced activity promotes hepatic lipogenesis, inhibits lipolysis, aggravates liver inflammation, and accelerates NAFLD progression
Further, acetylcarnitine facilitates acetylcholine production in the striatum and hippocampus 51
stimulated TNF--induced human bronchial epithelial (BEAS-2B) cells with varying doses of cis-9, trans-11-conjugated linoleic acid (c9,t11-CLA) and demonstrated that c9,t11-CLA significantly inhibited the secretion of inflammatory cytokines (e.g., IL-6, IL-8, MCP-1, and CCL5) and reduced the expression level of intercellular adhesion molecule 1 (ICAM-1), thereby attenuating monocyte adhesion to inflamed bronchial epithelial cells (102)
J Clin Invest (2010) 120:400720
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