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Targeting immune checkpoints MMR defect and immunotherapy response Tumors with defects in MMR genes or microsatellite instability (MSI) often have an enhanced antitumor immune response, displaying a higher density of tumor-infiltrating lymphocytes (TILs)
Retrieved from Federico, A., Cotticelli, G., Festi, D., et al
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Stable scores suggest adaptation to the current dose
Side Effects: Tachycardia, palpitations, eye pain, urinary retention, urinary tract infection and urticaria
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