25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines
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With weight reduction, GLP-1RA can improve dysregulated lipid profile and insulin resistance of individuals with obesity, thus reducing residual ASCVD risk [83,84,85]
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