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10.1007/s40265-022-01779-z 128 YeJ.ZhuN.SunR.LiaoW.FanS.ShiF.et al (2018)

Metallothionein-3 (MT3), a brain-specific metalloprotein, serves as a primary antioxidant that rapidly responds to oxidative stress

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As these therapies move from trials into everyday practice, which of these breakthroughs do you believe will have the most lasting impact on how medicine is practiced?

[72] Meta-analyses of melatonin for delayed sleep phase syndrome that found it effective have reported that it improves time to sleep onset by about 40 minutes (0.67 hours) and advances onset of endogenous melatonin secretion by about 1.2 hours (72 minutes)