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Back then, I had some hair but now I am completely bald because I was thinking way too much more than I had to
76 For instance, AARS1 functions as an intracellular lactate sensor, directly binding lactate to form lactate-AMP, and mediates lactylation of K120/139 on p53 within its DNA-binding domain (DBD), which prevents the binding of p53 to DNA containing p53 response elements (p53RE-DNA) and subsequent p53 liquidliquid phase separation (LLPS)
Many people experience nausea, early fullness, bloating, reflux, constipation, or diarrhea, especially when starting the medication or increasing the dose
"It's like my taste buds flipped." This change could be driven due to dimmed taste, Munger says
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