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However, comparisons between short and long term exposure of GLP-1R agonists in the presence of the GLP-1R antagonist Exendin-9, on neurite outgrowth, neuronal sensitivity and TRPV1 expression in thoracic and lumbosacral DRG are required, and will be the focus of future studies
According to the data provided by the Synapse Database, As of November 22, 2023, there are 39 investigational drugs for the GIPR and GLP-1R target, including 24 indications, 29 R&D institutions involved, with related clinical trials reaching 154, and as many as 1328 patents
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Similar experience has been reported in rats and mice in other studies (Lipsky et al
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