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If you were experiencing GI symptoms that you attributed to the medication itself, you may find that they improve at weekly dosing as drug concentrations settle into the tested therapeutic range

However, previous studies have not resolved certain questions: i) whether alterations in the identified proteins and metabolites are affected by eye drops, ii) how these changes in proteins and metabolites are affected by glaucoma phenotype, and iii) whether normal-tension glaucoma shows protein and metabolite changes in the same way as POAG

These are frequently reported during dose titration periods and often decrease over time as the body adjusts

Similar to injectable: nausea (47%), vomiting (31%), constipation (20%), diarrhea (18%), and abdominal pain (~15%)