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Both Mounjaro and Zepbound are once-weekly injections
The situation remains fluid
Primer sequences for AAEL002590 (Serine Protease) and the housekeeping gene (RPS17) can be found in Supplemental Materials 5
Using the social isolation with chronic restraint rat model, we confirmed that trimetazidine (30 mg/kg) injected once-daily for 2 weeks had an antidepressant-like effect shown by reduced immobility in the forced swim test
This is because it not only dilutes the drugs but also maintains their sterility over multiple uses
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