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GLP-1 therapy refers to using glucagon-like peptide-1 receptor agonists as a treatment for conditions like type 2 diabetes and obesity

The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcoming cytostatic-drug resistance is also a strong inhibitor of glyoxalase I

Before I recommend GLP-1 therapy, I screen for a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2, prior pancreatitis, significant gallstone disease, severe gastroparesis, and pregnancy or planned conception

These changes can lead to a lower risk of cardiovascular diseases and other obesity-related conditions

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