Ou Y, Cui Z, Lou S, Zhu C, Chen J, Zhou L, Zhao R, Wang L, Zou F
The active ingredient of Rybelsus is Semaglutide
In a phase 2 clinical trial for obesity, 26 weeks of efinopegdutide (doses 5 to 10mg) resulted in up to 11.8% WL in people with obesity (without diabetes) compared to 7.5% WL with liraglutide 3 mg and 1.8% WL with placebo [77, 78]
SeekPeptides members have access to detailed protocols for managing exactly these situations, with specific adjustment guidelines based on individual body composition data
Participation in a regulated clinical trial remains the only currently legitimate route to accessing retatrutide in the UK, and eligibility is determined by the trial protocol rather than standard prescribing criteria