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Reported EC values for MT-II in transfected cell assays fall in the sub-nanomolar to low-nanomolar range at MC1R and MC4R, roughly an order of magnitude weaker at MC3R and MC5R, and it is essentially inactive at MC2R, the adrenocorticotropin receptor
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Availability and FDA approval status This is perhaps the most practically important section of the entire comparison
The more useful question is not only how much, but how much, how often, and why that schedule. A practical comparison helps here
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