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PubMed , doi:10.1159/000130426
A., Fletcher, M., Hollinghurst, S., & Peters, T
([ref]Please read the full article for details): Article: Histamine intolerance : Studies have shown Luteolin to inhibit histamine release from mast cells.[ref] (Please read the full histamine intolerance article for details): Cautions with Luteolin: Article: COMT interaction: Luteolin is metabolized using the COMT enzyme , so individuals with slow COMT may want to use it with caution and watch for mood changes
As a topical cream, it works at the skins surface and may support the skins own renewal pathways
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