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Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12
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Confirm compatibility before reconstituting any compound
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Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)
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