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Second, indirect antibiotic potentiators act on other interdependent factors that contribute to resistance
Importantly, LSC-Exo significantly prevents SARS-CoV-2 infection in Syrian hamsters, a model of severe COVID-19 disease 35 , by a drastically reduced viral load, diminished lung inflammation, and dampened viral pneumonia
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In vivo and in vitro models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expression of genes related to glutathione anabolic metabolism (GCLC, GCLM, and SLC7A11) was significantly down-regulated
1998), sequestration of heavy metals (Cobbett and Goldsbrough 2002) and defense against ROS (Foyer and Noctor 2005a)
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