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It is not found circulating in blood at measurable concentrations
Initial Loading Dose Protocol For severe deficiency, the first dose is usually 1,000 mcg given intramuscularly
Brenner, J.T
Importantly, impaired hepatic metabolic function can compromise carnitine biosynthetic capacity, potentially leading to relative deficiency that may contribute to hepatic lipid accumulation, inflammatory activation, oxidative stress, and insulin resistance
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